Curcumenol 提取具有药用价值的Curcuma zedoaria,是高效的CYP3A4抑制剂(IC50=12.6 μM),具有神经抗肿瘤、保护、抗炎、和保肝的作用。它在 LPS 刺激的 BV-2 小胶质细胞中,抑制 Akt 介导的 NF-Κb 活化及 p38 MAPK 信号通路。
产品描述
Curcumenol, one of the major components of Zedoary turmeric oil, is an antibiotic drug which has anti-Y, anti-inflammation activity. Curcumenol may be safely used without inducing metabolic drug-drug interaction through P450 inhibition.
Cas No.
19431-84-6
分子式
C15H22O2
分子量
234.339
别名
(+)-Curcumenol;莪术醇
储存和溶解度
DMSO:196.3 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years