BB-Cl-Amidine 是一种肽基精氨酸脱胺酶抑制剂。

BB-Cl-Amidine is an inhibitor of peptidyl arginine deminase (PAD).

Treatment with BB-Cl-amidine subtly reduces splenomegaly in MRL/lpr mice, while there is a trend towards increased circulating levels of anti-NET antibodies with PAD inhibitor treatment. However, neither PAD inhibitor affected body weight or total IgG levels. The BB-Cl-amidine group also shows a strong trend towards the downregulation of IRGs. Treatment with BB-Cl-amidine significantly improves muzzle alopecia, in many cases preventing it entirely.

1802637-39-3

C26H26ClN5O

459.97

DMSO:124 mg/mL (269.58 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years