| CAS NO: | 155584-74-0 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| Molecular Weight (MW) | 262.74 |
|---|---|
| Formula | C13H15ClN4 |
| CAS No. | 155584-74-0 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 21 mg/mL (79.9 mM) |
| Water: <1 mg/mL | |
| Ethanol: 61 mg/mL (232.2 mM) | |
| SMILES | CN1CCN(CC1)C2=NC3=CC=CC=C3N=C2Cl |
| Synonyms | VUF 10166; VUF-10166; VUF10166; |
| In Vitro | In vitro activity: VUF10166 shows low activity to 5-HT3AB receptor with Ki of 22 nM. VUF10166 may be used to can distinguish between 5-HT3A and 5-HT3AB receptors. VUF10166 has no activity to α7 nACh receptor. VUF10166 also acts as a partial agonist at 5-HT3A receptors with EC50 of 5.2 μM, which shows that VUF10166 is unlikely to bind in the receptor pore. |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | J Pharmacol Exp Ther. 2012 May;341(2):350-9. |
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