TopiroxoSTAT 是一种有效的口服黄嘌呤氧化还原酶 (XOR) 抑制剂，IC50=5.3 nM，Ki=5.7 nM。它还表现出弱的CYP3A4抑制活性 (18.6%)。它有用于高尿酸血症的研究潜力。

Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.

577778-58-6

C13H8N6

248.24

托匹司他;FYX-051

DMSO:23.5 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years