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SJF 1521
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SJF 1521图片
CAS NO:2230821-40-4
包装:5mg
市场价:5072元

产品介绍
Cas No.2230821-40-4
Canonical SMILESCC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(COCCOCCOCCOC4=CC=C(C5=CC6=C(N=CN=C6NC7=CC(Cl)=C(C=C7)OCC8=CC(F)=CC=C8)C=C5)C=C4)=O)=O)O)=O)SC=N1
分子式C57H61ClFN7O9S
分子量1074.66
溶解度DMSO|107.47|100|
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Selective EGFR Degrader. Comprises the EGFR inhibitor lapatinib joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Exhibits selectivity for EGFR, including mutant forms, over HER2. Induces degradation of EGFR in OVCAR8 cells.