UK-371804 是一种尿嘧啶型纤溶酶原激活物的抑制剂，Ki=10 nM。

UK-371804 is an effective and specific uPA inhibitor. It was selected as a candidate for further preClinicalal evaluation for the treatment of chronic dermal ulcers.

在猪急性切除伤口模型中,局部给药UK-3718046可穿透猪伤口并抑制外源性uPA活性,对伤口愈合参数无副作用.

体外研究中,UK-3718046对人类慢性伤口液中的外源性uPA有抑制作用（IC50：0.89 μM）。

256477-09-5

C14H16ClN5O4S

385.82

UK371804

DMSO:10 mg/mL (25.92 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years