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Zearalenone-13C18
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Zearalenone-13C18图片
CAS NO:911392-43-3
包装:1.2 ml
市场价:14742元

产品介绍
An internal standard for the quantification of zearalenone
Cas No.911392-43-3
别名玉米烯酮-(全碳-13)
Canonical SMILESO[13C]1=[13C]([13C](O[13C@@H]([13CH3])[13CH2][13CH2][13CH2][13C]([13CH2][13CH2][13CH2]/[13CH]=[13CH]/2)=O)=O)[13C]2=[13CH][13C](O)=[13CH]1
分子式[13C]18H22O5
分子量336.2
溶解度Acetonitrile: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Zearalenone-13C18is intended for use as an internal standard for the quantification of zearalenone by GC- or LC-MS. Zearalenone is a mycotoxin that has been found inFusariumand has estrogenic activities.1It binds to human estrogen receptor α (ERα) and ERβ (IC50s = 9 and 5.8 nM, respectively).2Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.3Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also induces degeneration of meiotic chromatin in oocytes and reduces fertility in pigs when administered at a dose of 200 µg/kg.4Zearalenone has been found as a contaminant in wheat, maize, and barley and livestock feeds.3,4

1.Zinedine, A., Soriano, J.M., MoltÓ, J.C., et al.Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An oestrogenic mycotoxinFood Chem. Toxicol.45(1)1-18(2007) 2.Kuiper, G.G.J.M., Lemmen, J.G., Carlsson, B., et al.Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor βEndocrinology139(10)4252-4263(1998) 3.Richard, J.L.Some major mycotoxins and their mycotoxicoses—an overviewInt. J. Food Microbiol.119(1-2)3-10(2007) 4.Tiemann, U., and DÄnicke, S.In vivo and in vitro effects of the mycotoxins zearalenone and deoxynivalenol on different non-reproductive and reproductive organs in female pigs: A reviewFood Addit. Contam.24(3)306-314(2007)