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Dodecyl Gallate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dodecyl Gallate图片
CAS NO:1166-52-5
包装与价格:
包装价格(元)
25 g电议
50 g电议
100 g电议
250 g电议

产品介绍
没食子酸十二烷基酯(Lauryl gallate)已被广泛用作食品制造以及制药和化妆品行业的抗氧化剂。
Cas No.1166-52-5
别名没食子酸月桂酯,Lauryl gallate
Canonical SMILESO=C(C1=CC(O)=C(C(O)=C1)O)OCCCCCCCCCCCC
分子式C19H30O5
分子量338.4
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:2): 0.3 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dodecyl gallate is a derivative of the antioxidant gallic acid that has diverse biological activities, including antioxidant, antiproliferative, and antibacterial properties.1,2,3It inhibits proliferation of a variety of cancer cells, including WEHI-231 mouse B cell lymphoma, Daudi human lymphoma, and HT-29 human colon cancer cells (IC50s = 0.8, 1.4, and 17.0 µM, respectively).1It induces apoptosis of WEHI-231 cells but not L-929 mouse fibroblasts. Dodecyl gallate decreases peroxidation of ox brain phospholipid liposomes by 71 and 76% when used at concentrations of 12 and 50 µM, respectively, and scavenges trichloromethyl peroxyl radicals at 0.05% w/v.2It is active against a variety of Gram-positive bacteria, includingB. subtilis(MIC = 25 µg/ml), as well asM. luteus,S. aureus, and methicillin-resistantS. aureus(MRSA; MICs = 12.5 µg/ml for all), and acts by inhibiting the bacterial membrane respiratory chain.3

1.Serrano, A., Palacios, C., Roy, G., et al.Derivatives of gallic acid induce apoptosis in tumoral cell lines and inhibit lymphocyte proliferationArch. Biochem. Biophys.350(1)49-54(1998) 2.Aruoma, O.I., Murcia, A., Butler, J., et al.Evaluation of the antioxidant and prooxidant actions of gallic acid and its derivativesJ. Agric. Food Chem.41(11)1880-1885(1993) 3.Kubo, I., Fujita, K.-i., Nihei, K.-i., et al.Non-antibiotic antibacterial activity of dodecyl gallateBioorg. Med. Chem.11(4)573-580(2003)