IDH1-IN-1 是IDH1突变体的选择性抑制剂，能够作用于突变体IDH1 R132C/R132C (IC50:4 nM) ，IDH1 R132H/R132H (IC50:42 nM) ，IDH1 R132H/WT (IC50:80 nM) 和野生型IDH1 (IC50:143 nM)。

Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50< 0.1 uM.

1355326-21-4

C30H31FN4O2

498.602

IDH1-IN-1

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years