RS 61443 是一种免疫抑制剂,一种非竞争性、选择性和可逆的肌苷一磷酸脱氢酶 (IMPDH) 抑制剂。
产品描述
RS 61443 is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)
体外活性
Mycophenolate mofetil (MMF) is a relatively new systemic immunosuppressive agent whose use is rapidly increasing within the field of dermatologic.?Originally used in the 1970s for the treatment of psoriasis, MMF has demonstrated efficacy in multiple types of inflammatory skin diseases.?Although the safety data within the dermatologic literature is sparse, MMF's extensive use within the field of organ transplantation has demonstrated a favorable safety profile.?MMF's lack of hepatic or renal toxicity is a significant advantage over immunosuppressive medications currently used in dermatology and make MMF an attractive candidate for multidrug regimens.
Cas No.
115007-34-6
分子式
C23H31NO7
分子量
433.5
别名
Mycophenolate mofetil;吗替麦考酚酯;RS61443;TM-MMF
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years