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PACMA 31
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PACMA 31图片
CAS NO:1401089-31-3
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Cas No.1401089-31-3
Canonical SMILESO=C(C#C)N(C(C2=CC=CS2)C(NCC(OCC)=O)=O)C1=CC=C(OC)C=C1OC
分子式C21H22N2O6S
分子量430.47
溶解度DMSO: 100 mM
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
产品描述

Irreversible protein disulfide isomerase (PDI) inhibitor; inhibits growth of ovarian cancer cells. Suppresses tumor growth in a mouse xenograph model of human ovarian cancer.

Ge et al (2013) Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase. ACS.Chem.Biol. 8 2577 PMID:24070012 |Xu et al (2012) Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment. Proc.Natl.Acad.Sci.U.S.A. 109 16348 PMID:22988091