您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Tetrazine-PEG4-SS-NHS
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Tetrazine-PEG4-SS-NHS
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tetrazine-PEG4-SS-NHS图片
包装:10mg
市场价:3870元

产品介绍
Tetrazine-PEG4-SS-NHS是一种可降解(cleavable)的含4个单元PEG的ADClinker,可用于合成抗体偶联药物(ADC)。
Canonical SMILESO=C(CCOCCOCCOCCOCCNC(CCSSCCC(ON1C(CCC1=O)=O)=O)=O)NCC(C=C2)=CC=C2C3=NN=CN=N3
分子式C30H41N7O10S2
分子量723.82
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.