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RPR132595A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
RPR132595A图片
CAS NO:185304-42-1
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
RPR132595A(NPC)是CPT-11的活性代谢产物,它是由细胞色素P-4503A4(CYP3A4)产生并最终通过尿排出。
Cas No.185304-42-1
别名NPC
Canonical SMILESO=C(N1CCC(N)CC1)OC2=CC=C3N=C4C(CN5C(C(COC([C@@]6(CC)O)=O)=C6C=C54)=O)=C(CC)C3=C2
分子式C28H30N4O6
分子量518.56
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

RPR132595A (NPC) is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine[1].

[1]. Alvau MD, et al. Enzyme-Based Electrochemical Biosensor for Therapeutic Drug Monitoring of Anticancer Drug Irinotecan.Anal Chem. 2018 May 15;90(10):6012-6019.