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(1R,2R)-2-PCCA hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(1R,2R)-2-PCCA hydrochloride图片
CAS NO:1609563-71-4
包装与价格:
包装价格(元)
25 mg电议
50 mg电议

产品名称
(1R,2R)-2-PCCA(hydrochloride)
产品介绍

产品描述

(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and is a potent agonist of GPR88 receptor(EC50 of 3 nM and 603 nM in cell-free assay and in cell assay).

体外活性

(1R,2R)-2-PCCA is a potent agonist of GPR88 receptor(EC50 of 3 nM in cell-free assay, and 603 nM in cell assay)[1][2]. (1R,2R)-2-PCCA inhibits GPR88-mediated cAMP production through a Gαi-coupled pathway, with an EC50 of 56 nM in HEK293 cells stably expressing the human GPR88 receptor and the GloSensor-22F cAMP construct[2].

Cas No.

1609563-71-4

分子式

C30H39Cl2N3O

分子量

528.56

别名

(1R,2R)-2-PCCA(hydrochloride)

储存和溶解度

DMSO:50 mg/mL (94.60 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years