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Antidepressant agent 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Antidepressant agent 1图片
CAS NO:67411-41-0
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Antidepressant agent 1 是一种具有抗抑郁作用的吡唑啉-卤素衍生物,也可用于提高体温。
Cas No.67411-41-0
Canonical SMILESCCN1CCN2C3=C(C4=C2C1CCC4)C=C(Br)C=C3
分子式C16H19BrN2
分子量319.24
溶解度DMSO: 8.93 mg/mL (27.97 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Antidepressant agent 1 is a pyrazidole-halogeno-derivative with antidepressant effects. Antidepressant agent 1 also can be used to increase body temperature[1].

Antidepressant agent 1 (compound I) is prepared in 56% yields by reduction of compound II by NaBH4-AcOH. Compound II is obtained by condensation of compound III with BrCH2CH(OBu)2 followed by acid-catalyzed cyclization[1].

[1]. V. I. Shvedov, et al. Synthesis and properties of new analogs of pyrazidole-halogeno-derivatives of 1,10-trimethylene-2-ethyl-1,2,3,4-tetrahydropyrazino [1,2-a]indole. Pharmaceutical Chemistry Journal volume 12, pages633-635(1978).