| CAS NO: | 361154-30-5 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 25mg | 电议 |
Ac4ManNAz 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
| Cas No. | 361154-30-5 |
| 别名 | 1,3,4,6-四-O-乙酰基-N-叠氮乙酰基氨基甘露糖 |
| Canonical SMILES | O=C(N[C@@H]1C(OC(C)=O)O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O)CN=[N+]=[N-] |
| 分子式 | C16H22N4O10 |
| 分子量 | 430.37 |
| 溶解度 | DMSO:100 mg/mL (232.36 mM; Need ultrasonic) |
| 储存条件 | Store at 2-8℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Ac4ManNAz is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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