TelotriSTAT etiprate 是一种色氨酸羟化酶抑制剂，可抑制血清素的产生。

Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.

Telotristat Etiprate (300 mg/kg p.o.) significantly reduces 5-HT in the gut and blood, but not brain 5-HT. Telotristat Etiprate (200 mg/kg p.o.) alleviates the severity of trinitrobenzene sulfonic acid (TNBS)-induced colitis with lower expression of some genes encoding inflammation-related cytokines and chemokines in mice. [2]

1137608-69-5

C36H35ClF3N7O6

754.16

特罗司他马尿酸盐;LX1606 (Hippurate);LX 1606 Hippurate

Ethanol:<1 mgml
H2O:<1 mgml
DMSO:100 mg/mL (132.59 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years