EC5026 是首创的，非阿片类的，可溶性环氧水解酶 (sEH) 抑制剂，它可有效缓解发炎性和神经性疼痛。

EC5026 has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.

EC5026 (BPN-19186) is a first-in-class, small molecule that potently inhibits soluble Epoxide Hydrolase (sEH), a key regulatory enzyme involved in the metabolism of membrane fatty acids.?Inhibition of sEH treats pain by stabilizing natural analgesic and anti-inflammatory mediators.?sEH inhibitors developed by EicOsis have already shown efficacy for treating pain with no apparent adverse or addictive effects in laboratory animals and relieving naturally occurring pain in dogs, cats and horses.

1809885-32-2

C18H23F4N3O3

405.39

BPN-19186

DMSO:250 mg/mL (616.69 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years