OncRasin 1 是一种有效的抗癌抑制剂,可在低或亚微摩尔浓度下杀死具有 K-Ras 突变的各种人类肺癌细胞。
产品描述
Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations
体内活性
In vivo administration of oncrasin-1 suppressed the growth of K-ras mutant human lung tumor xenografts by >70% and prolonged the survival of nude mice bearing these tumors, without causing detectable toxicity[1].
Cas No.
75629-57-1
分子式
C16H12ClNO
分子量
269.73
别名
1-(4-氯苄基)-1H-吲哚-3-甲醛
储存和溶解度
DMSO:43 mg/mL (159.42 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years