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N-Boc-PEG3-bromide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-Boc-PEG3-bromide图片
CAS NO:165963-71-3
包装:100mg
市场价:2700元

产品介绍
N-Boc-PEG3-bromide是一种可降解(cleavable)的ADClinker,用于抗体偶联药物(ADCs)的合成。
Cas No.165963-71-3
别名(2-(2-(2-溴乙氧基)乙氧基)乙基)氨基甲酸叔丁酯
Canonical SMILESCC(C)(OC(NCCOCCOCCBr)=O)C
分子式C11H22BrNO4
分子量312.2
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-Boc-PEG3-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[1]. Alex Cortez, et al. Antibody conjugates comprising toll-like receptor agonist and combination therapies. WO2018198091A1.