CAS NO: | 315702-40-0 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Cas No. | 315702-40-0 |
Canonical SMILES | CN1C(NN=C1CSC2=NC3=CC=CC=C3S2)=S |
分子式 | C11H10N4S3 |
分子量 | 294.42 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Selective MRP (multidrug resistance-associated protein) 4 inhibitor (IC50 = 2.6 μM). Selective for MRP4 over P-gp, MRP1 and ABCG2. Sensitizes MRP4 over-expressing cells to SN 38 . Cheung et al (2014) High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4). Biochem.Pharmacol. 91 97 PMID:24973542 |