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Territrem A
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Territrem A图片
CAS NO:70407-19-1
包装与价格：
包装价格(元)
500μg电议
2.5mg电议

产品介绍
A mycotoxin and AChE inhibitor
Cas No.70407-19-1
Canonical SMILESO=C1C=CC(C)(C)[C@]([C@@]21C)(O)CC[C@@]([C@]2(O)C3)(C)OC4=C3C(OC(C5=CC(OCO6)=C6C(OC)=C5)=C4)=O
分子式C28H30O9
分子量510.5
溶解度DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Territrem A is a mycotoxin originally isolated from A. terreus that irreversibly inhibits acetylcholinesterase (AChE; IC50 = 24 nM for the electric eel enzyme).1 It is toxic to mice, inducing tremors with a median tremulous dose of 0.31 mg/kg, and has an LD50 value of 17.6 mg/kg.2

|1. Chen, J.-W., and Ling, K.-H. Territrems: Naturally occurring specific irreversible inhibitors of acetylcholinesterase. J. Biomed. Sci. 3(1), 54-58 (1996).|2. Ling, K.H., Liou, H.-H., Yang, C.-M., et al. Isolation, chemical structure, acute toxicity, and some physicochemical properties of territrem C from Aspergillus terreus. Appl. Environ. Microbiol. 47(1), 98-100 (1984).