OGG1-IN-O8 是一种有效的 8-oxoguanine DNA 糖基化酶-1 (OGG1) 抑制剂，IC50 值为 0.22 μM.
| Cas No. | 350997-39-6 |
| Canonical SMILES | ClC1=C(C(Cl)=C(C(NN)=O)S2)C2=CC=C1 |
| 分子式 | C9H6Cl2N2OS |
| 分子量 | 261.1 |
| 溶解度 | DMF: 5mg/mL,DMSO: 10mg/mL,DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | OGG1-IN-O8 is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1; IC50 = 0.35 μM).1 It is selective for OGG1 over Nei-like DNA glycosylase 1 (NEIL1), endonuclease III homolog 1 (NTH1), and formamidopyrimidine DNA glycosylase (Fpg) at 50 μM. |
m.cnreagent.com