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Promestriene
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Promestriene图片
CAS NO:39219-28-8
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
Promestriene 是一种合成的雌二醇二乙醚，是一种局部有效的雌激素。Promestriene 对阴道萎缩有有效的治疗作用，但吸收量小。
Cas No.39219-28-8
别名普罗雌烯
Canonical SMILESC[C@@]12[C@@H](OC)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OCCC)=C4)[C@@]3([H])CC2
分子式C22H32O2
分子量328.49
溶解度DMSO: 20 mg/mL (60.88 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Promestriene is a synthetic diethyl-ether of estradiol and a locally effective estrogen. Promestriene has an efficient action on vaginal atrophy while it is minimally absorbed [1][2].

[1]. Isabel Santos, et al. Urogenital Disorders Associated With Oestrogen Deficiency: The Role of Promestriene as Topical Oestrogen Therapy. Gynecol Endocrinol. 2010 Sep;26(9):644-51. [2]. Lino Del Pup, et al. Promestriene, a Specific Topic Estrogen. Review of 40 Years of Vaginal Atrophy Treatment: Is It Safe Even in Cancer Patients. Anticancer Drugs. 2013 Nov;24(10):989-98. [3]. AJO Almodovar, et al. Abstract P5-05-07: Promestriene effects on estrogen-sensitive breast cancer cell proliferation in vitro. Cancer Res 2013;73(24 Suppl): Abstract nr P5-05-07.