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Glyco-diosgenin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glyco-diosgenin图片
CAS NO:1402423-29-3
包装:10mg
市场价:990元

产品介绍
Glyco-diosgenin是一种合成的表面活性剂和去污剂,用于从膜中提取蛋白质以进行结构和功能研究,以及对膜蛋白质进行单粒子冷冻电子显微镜(cryoEM)研究。
Cas No.1402423-29-3
别名糖酵素(GDN)
Canonical SMILESC[C@@]([C@@]1([H])C2)(CC[C@@]3([H])[C@@]1([H])CC=C(C4)[C@@]3(CC[C@@H]4OCCC(CO[C@@H]([C@@H]([C@H]5O)O)O[C@@H]([C@H]5O[C@H]([C@@H]([C@H]6O)O)O[C@@H]([C@H]6O)CO)CO)CO[C@@H]([C@@H]([C@H]7O)O)O[C@@H]([C@H]7O[C@H]([C@@H]([C@H]8O)O)O[C@@H]([C@H]8O)CO)CO)C)[C@]9([H])[C@@]2([H])O[C@@](CC[C@H]%10C)(OC%10)[C@H]9C
分子式C56H92O25
分子量1165.31
溶解度DMSO: 100 mg/mL (85.81 mM)
储存条件4℃, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Glyco-diosgenin is a synthetic surfactant and detergent for extracting proteins from membranes for structure and function studies, and single-particle cryo-electron microscopy (cryoEM) studies of membrane proteins[1][2].

Glyco-diosgenin (16 h) solubilizes and purifies the twin arginine translocation BC (TatBC) complex[1].

[1]. Dalsen L, et, al. In meso crystallogenesis. Compatibility of the lipid cubic phase with the synthetic digitonin analogue, glyco-diosgenin. J Appl Crystallogr. 2020 Mar 25;53(Pt 2):530-535. [2]. Wojnowska M,et, al. Precursor-Receptor Interactions in the Twin Arginine Protein Transport Pathway Probed with a New Receptor Complex Preparation. Biochemistry. 2018 Mar 13;57(10):1663-1671.