CAS NO: | 2141981-86-2 |
包装 | 价格(元) |
25mg | 电议 |
50mg | 电议 |
Cas No. | 2141981-86-2 |
Canonical SMILES | O=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCC(O)=O |
分子式 | C18H31NO7 |
分子量 | 373.44 |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | TCO-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. |