Levolansoprazole 是一种质子泵抑制剂,不可逆地抑制壁细胞中 H+/K+ 刺激的 ATPase 泵 (IC50: 5.2 μM)。它还抑制分离的犬壁细胞中的酸形成(IC50:82 μM)。 (R)-和 (S)-兰索拉唑均具有药理活性,具有相似的效力。
产品描述
Levolansoprazole, a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 μM). It also inhibits acid formation in isolated canine parietal cells (IC50: 82 μM). Both (R)- and (S)-lansoprazole are pharmacologically active with similar potencies.
Cas No.
138530-95-7
分子式
C16H14F3N3O2S
分子量
369.36
别名
左旋兰索拉唑;(S)-Lansoprazole;(-)-Lansoprazole
储存和溶解度
DMSO:55 mg/ml (148.91 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years