O4I2 是一种OCT3/4诱导剂,可增强多能干细胞相关基因Lin28、Sox2和Nanog的表达,并抑制Rex1。
产品描述
O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.
体外活性
O4I2 activates Oct3/4 expression in HEK293 and embryonal NCCIT cells, and also in Oct-deficient HeLa and terminally differentiated human fibroblasts, and also induces other pluripotency-associated genes such as Lin28 and Nanog. [1]
Cas No.
165682-93-9
分子式
C12H11ClN2O2S
分子量
282.74
储存和溶解度
Ethanol:14.1 mg/mL (50 mM)
DMSO:28.3 mg/mL (100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years