N-Succinimidyloxycarbonylpropyl methanethiosulfonate

您好，欢迎来到化工原料网！ [登录] [免费注册]

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品介绍

N-Succinimidyloxycarbonylpropyl methanethiosulfonate 是一种不可降解 (non-cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

Cas No.	690632-55-4
别名	NHS-C4-MTS
Canonical SMILES	O=C(ON1C(CCC1=O)=O)CCCSS(=O)(C)=O
分子式	C₉H₁₃NO₆S₂
分子量	295.33
溶解度	Soluble in DMSO
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	N-Succinimidyloxycarbonylpropyl methanethiosulfonate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.