VX-661 是一种小分子，可用作囊性纤维化跨膜电导调节器基因功能的校正剂。

VX-661 is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.

F508del突变通道能够在VX-661的作用下,避免被降解并转运至细胞膜上。

1152311-62-0

C26H27F3N2O6

520.5

1-(2,2-二氟-1,3-苯并二氧戊环-5-基)-N-[1-[(2R)-2,3-二羟基丙基]-6-氟-2-(2-羟基-1,1-二甲基乙基)-1H-吲哚-5-基]-环丙烷甲酰胺;VX661

Ethanol:<1 mgml
H2O:<1 mgml
DMSO:93 mg/mL (178.7 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years