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8pyDTZ
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
8pyDTZ图片
CAS NO:2351898-91-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
8pyDTZ 是一种吡啶基二苯基叔嗪 (DTZ) 类似物,也是 一种 LumiLuc 荧光素酶的 ATP 非依赖性吡啶基底物。8pyDTZ 表现出光谱偏移的发射并改善了水溶性。8pyDTZ 具有出色的生物相容性和体内敏感性,可用于生物体内发光成像。
Cas No.2351898-91-2
Canonical SMILESO=C1C(CC2=CC=CC=C2)=NC3=C(C4=CC=NC=C4)NC(C5=CC=CC=C5)=CN31
分子式C24H18N4O
分子量378.43
溶解度DMSO: 12.5 mg/mL (33.03 mM; DMSO can inactivate 8pyDTZ's activity); EtOH+HCl: 2 mg/mL (5.28 mM; ultrasonic and adjust pH to 2 with 1M HCl; DMSO can inactivate 8pyDTZ's activity); Water:< 0.1 mg/mL (insoluble; DMSO can inactivate 8pyDTZ's activity)
储存条件Store at -20°C,unstable in solution, ready to use.
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

8pyDTZ is a pyridyl diphenylterazine (DTZ) analog and an ATP-independent pyridyl substrate of LumiLuc luciferase. 8pyDTZ exhibits spectrally shifted emission and improved water solubility. 8pyDTZ has excellent biocompatibility and superior in vivo sensitivity. 8pyDTZ can be used for in vivo luminescence imaging[1].

[1]. Yeh HW, et al. ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging. ACS Chem Biol. 2019 May 17;14(5):959-965.