Loureirin A 是一种黄酮类物质，从龙血树中分离得到，能够降低Akt的磷酸化，具有抗血小板聚集作用。

Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs.

119425-89-7

C17H18O4

286.327

龙血素 A;龙血素A

DMSO:86.6 mg/mL (302.46 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years