Bumetanide D5 is a deuterated form of Bumetanide. Bumetanide is a specific Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively. References: [1]. Sandstrom PE1, et al. Evidence for diabetogenic action of bumetanide in mice.Eur J Pharmacol. 1988 May 20;150(1-2):35-41.
纯度:≥98%
CAS:1216739-35-3