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GS-443902
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GS-443902图片
CAS NO:1355149-45-9
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
瑞德西韦代谢物
产品介绍
Remdesivir triphosphate是一种有效的病毒 RNA 依赖的 RNA 聚合酶抑制剂,对RSVRdRp 和 HCVRdRp 的IC50分别为 1.1 μM 和 5 μM。它是 Remdesivir 的活性三磷酸代谢物。

产品描述

Remdesivir triphosphate is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp) with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir.

动物实验

Cats ranged from 3.4–73 months of age (mean 13.6 months); 26 had effusive or dry-to-effusive FIP and five had non-effusive disease. Cats with severe neurological and ocular FIP were not recruited. The group was started on GS-441524 at a dosage of 2.0 mg/kg SC q24h for at least 12 weeks and increased when indicated to 4.0 mg/kg SC q24h.

Cas No.

1355149-45-9

分子式

C12H16N5O13P3

分子量

531.203

别名

瑞德西韦代谢物

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years