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KKL-10
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
KKL-10图片
CAS NO:952849-76-2
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
KKL 10
产品介绍
KKL-10 是一种核糖体拯救抑制剂,对细菌具有广谱抗菌活性。

产品描述

KKL-10, a ribosome rescue inhibitor, has broad-spectrum antimicrobial activity against bacteria.

体外活性

KKL-10 shows markedly antimicrobial activity against both fully and attenuated virulent strains of F. tularensis. The MIC against F. tularensis strain Schu S4 and LVS are 0.48 and 0.12 μg/mL, respectively. KKL-10 inhibits the intracellular growth of F. tularensis during all stages of infection. KKL-10 cannot affect macrophage function or viability. KKL-10 (17.5 μg/mL) produces cytotoxic effects of less than 5%. The combination of IFN-γ stimulation and KKL-10 can reduce the bacterial load by >99.9%. KKL-10 also inhibits the growth of F. tularensis inside eukaryotic cells and exhibits no toxicity to HepG2 cells.

Cas No.

952849-76-2

分子式

C14H10BrN3O2S

分子量

364.22

别名

KKL 10

储存和溶解度

DMSO:6.8 mg/mL (18.67 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years