CAS NO: | 629-11-8 |
包装: | 10 g |
市场价: | 720元 |
Cas No. | 629-11-8 |
别名 | 1,6-己二醇 |
Canonical SMILES | OCCCCCCO |
分子式 | C6H14O2 |
分子量 | 118.18 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Widely used tool to probe liquid-liquid phase separation (LLPS) in cells. Disrupts hydrophobic interaction-induced phase separation assemblies both in vitro and in vivo. Dissolves LLPS condensates, such as P bodies, but not solid-like condensates, such as protein aggregates and cytoskeletal assemblies.Typically used as a 3-10% solution (w/v). Disrupts cellular structures in yeast and alters cellular morphology in HeLa cells. Shan et al (2018) Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division. Nat.Commun. 9 737 PMID:29467404 |Wheeler et al (2016) Distinct stages in stress granule assembly and disassembly. Elife 5 e18413 PMID:27602576 |Kroschwald et al (2017) Hexanediol: a chemical probe to investigate the material properties of membrane-less compartments. Matters |