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1,6-Hexanediol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1,6-Hexanediol图片
CAS NO:629-11-8
包装:10 g
市场价:720元

产品介绍
Tool for probing liquid-liquid phase separation
Cas No.629-11-8
别名1,6-己二醇
Canonical SMILESOCCCCCCO
分子式C6H14O2
分子量118.18
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Widely used tool to probe liquid-liquid phase separation (LLPS) in cells. Disrupts hydrophobic interaction-induced phase separation assemblies both in vitro and in vivo. Dissolves LLPS condensates, such as P bodies, but not solid-like condensates, such as protein aggregates and cytoskeletal assemblies.Typically used as a 3-10% solution (w/v). Disrupts cellular structures in yeast and alters cellular morphology in HeLa cells.

Shan et al (2018) Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division. Nat.Commun. 9 737 PMID:29467404 |Wheeler et al (2016) Distinct stages in stress granule assembly and disassembly. Elife 5 e18413 PMID:27602576 |Kroschwald et al (2017) Hexanediol: a chemical probe to investigate the material properties of membrane-less compartments. Matters