CLP-3094 是一种雄激素受体 BF3(binding function 3) 抑制剂，是一种选择性GPR142拮抗剂。BF3-IN-1 抑制 AR 转录活性 (IC50:4 μM)。

CLP-3094 is a potent androgen receptor BF3 (binding function 3) inhibitor. BF3-IN-1 inhibits AR transcriptional activity with IC50 of 4 μM. CLP-3094 is a selective and potent GPR142 antagonist.

I.p. administration of 30, 100 mg/kg CLP-3094 daily from Day 0 to Day 11 consistently displayed significantly lower severity of arthritis scores than vehicle-treated mice and reduced the arthritis scores dose-dependently, by not much.[2].

312749-73-8

C15H13ClN2OS

304.8

2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE

DMSO:100 mg/mL (328.09 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years