DehydroepiandROSterone 3-acetate 是一种雄性激素/雌性激素的前体物质,是一种由肾上腺皮质产生的主要 C19 类固醇,能够调节脊椎动物的攻击性行为。
产品描述
Dehydroepiandrosterone acetate is a primary C19 steroid generated by the adrenal cortex.
体内活性
Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of birds implanted with Dehydroisoandrosterone display higher aromatase mRNA expression in the preoptic area (POA) as well as higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels[1]. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group[2].
Cas No.
853-23-6
分子式
C21H30O3
分子量
330.468
别名
Prasterone acetate;DHEA acetate;androstenolone acetate;醋酸去氢表雄酮;Dehydroepiandrosterone 3-acetate;Dehydroepiandrosterone acetate
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years