Methimazole 是抗甲状腺化合物,具有显著的肝毒性,常用于研究甲亢。
产品描述
Methimazole is a thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
Cas No.
60-56-0
分子式
C4H6N2S
分子量
114.17
别名
甲巯咪唑;Thiamazole;Tapazole
储存和溶解度
Ethanol:22 mg/mL (192.7 mM)
DMSO:22 mg/mL (192.7 mM)
H2O:21 mg/mL (183.9 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years