Levothyroxine sodium 是一种合成的甲状腺激素，用于研究甲状腺功能减退症。DIO 酶能够将Levothyroxine 转化成具有生物活性的三碘甲状腺氨酸 (T3)。

Levothyroxine, the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.

evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR[1]

Cell lines: LS180V cells. Concentrations: 100 nM and 100μM. Incubation Time: 72 h. Method: LS180V cells are induced for 72 h with two l-T4 concentrations of 100 nM and 100 μM.

Animal Models: SD rats. Dosages: 20 μg/kg/day and 100 μg/kg/day. Administration: i.p.

55-03-8

C15H11I4NNaO4

799.86

LT4 sodium;左旋甲状腺素钠;L-T4 sodium;Levothyroxine sodium

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years