Obacunone是从沼泽白葡萄柚种子中分离得到的,通过诱导凋亡发挥抗癌作用。它在雄激素依赖性人前列腺 Y 细胞中具有细胞毒性。它对鼠伤寒沙门氏菌具有抗毒作用,可作为开发鼠伤寒沙门氏菌抗毒策略的先导化合物。
产品描述
Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the potential to prevent estrogen-responsive breast Y through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis.
Cas No.
751-03-1
分子式
C26H30O7
分子量
454.5
储存和溶解度
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
DMSO:82 mg/mL(180.4 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years