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P-Hydroxycinnamic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
P-Hydroxycinnamic acid图片
CAS NO:7400-08-0
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
对羟基肉桂酸
NSC 59260
p-Hydroxy-cinnamic acid
p-Coumaric acid
p-Cumaric acid
产品介绍
p-Hydroxycinnamic acid 是常见的食用酚,可抑制血小板活性,对血栓素 B2 和前列腺素 E2 的IC50值分别为 371 和 126 μM。

产品描述

p-Hydroxycinnamic acid can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.

体外活性

p-Hydroxycinnamic acid (500 μM and 1 mM) reduces ADP-induced platelet aggregation (55?2 (SE 4?01) % and 35?6 (SE 2?35) % relative to the basal level, respectively). p-Hydroxycinnamic acid is able to modify platelet function, a shear-inducing device that simulates primary hemostasis. p-Hydroxycinnamic acid interferes also with arachidonic acid cascade, reducing thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation (IC50 371 and 126 μM, respectively)[1].

Cas No.

7400-08-0

分子式

C9H8O3

分子量

164.16

别名

对羟基肉桂酸;NSC 59260;p-Hydroxy-cinnamic acid;p-Coumaric acid;p-Cumaric acid

储存和溶解度

DMSO:201 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years