KGP94 是一种有效的、选择性的和竞争性的溶酶体内肽酶抑制剂。
产品描述
KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.
体外活性
The novel cathepsin L/K inhibitors KGP94 could inhibit in vitro M2 macrophage invasion and reduce the macrophage-stimulated invasion of 4T1 murine breast cancer cells. KGP94 treatment also reduced the expression of several M2-associated markers, suggesting that cathepsin L activity may be important for IL-4-driven M0 to M2 differentiation[1].
Cas No.
1131456-28-4
分子式
C14H12BrN3OS
分子量
350.23
别名
KGP-94;KGP 94
储存和溶解度
DMSO:60 mg/ml (171.32 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years