Esomeprazole 是奥美拉唑(omeprazole) 的S-异构体,抑制溶酶体半胱氨酸蛋白酶legumain,防止癌症转移。它是一种质子泵抑制剂(PPI)。
产品描述
Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI).
体内活性
In an orthotopic transplantation nude mouse model, Esomeprazole reduced lung metastasis of MDA-MB-231 breast cancer cells[1].
Cas No.
119141-88-7
分子式
C17H19N3O3S
分子量
345.42
储存和溶解度
DMSO:15 mg/mL (43.43 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years