您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Diethylene Glycol Monobenzyl Ether
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Diethylene Glycol Monobenzyl Ether
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Diethylene Glycol Monobenzyl Ether图片
CAS NO:2050-25-1
包装:500mg
市场价:450元

产品介绍
DiethyleneGlycolMonobenzylEther是一种PROTAClinker,属于PEG类。可用于合成PROTAC分子。
Cas No.2050-25-1
别名2-[2-(苯基甲氧基)乙氧基]乙醇
Canonical SMILESOCCOCCOCC1=CC=CC=C1
分子式C11H16O3
分子量196.24
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Diethylene Glycol Monobenzyl Ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562