| CAS NO: | 7460-82-4 |
| 包装: | 500mg |
| 市场价: | 450元 |
| Cas No. | 7460-82-4 |
| 别名 | 二乙二醇双对甲苯磺酸酯,Diethylene glycol di(p-toluenesulfonate); Bis-Tos-PEG2 |
| Canonical SMILES | O=S(C1=CC=C(C)C=C1)(OCCOCCOS(C2=CC=C(C)C=C2)(=O)=O)=O |
| 分子式 | C18H22O7S2 |
| 分子量 | 414.49 |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. |
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