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DBCO-CONH-S-S-NHS ester
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
DBCO-CONH-S-S-NHS ester图片
CAS NO:1435934-53-4
包装与价格：
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
DBCO-CONH-S-S-NHSester是一种可降解(cleavable)的ADClinker，可用于合成抗体偶联药物(ADC)。
Cas No.1435934-53-4
Canonical SMILESO=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCSSCCC(ON4C(CCC4=O)=O)=O)=O
分子式C28H27N3O6S2
分子量565.66
储存条件4°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.