Seneciphylline 是一种有毒的吡咯烷核生物碱,存在于千里光植物中。它显著增加了环氧水合酶和谷胱甘肽-S-转移酶的特性,但导致细胞色素 P-450 和相关单加氧酶特性的抑制。
产品描述
Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutathione-S-transferase but cause reduction of cytochrome P-450 and related monooxygenase activities.
Cas No.
480-81-9
分子式
C18H23NO5
分子量
333.38
别名
千里光非灵;千里光菲灵碱
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years