Praeruptorin C 是白花前胡中的一种主要成分,是钙拮抗剂,pD2′值为 5.7。
产品描述
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors and regulating the Bcl-2 family. 3. Praeruptorin C can reduce vascular hypertrophy in isolated rat hypertrophied smooth muscle cells, and this is associated with improvement of smooth muscle cells [Ca2+]i level, nitric oxide content and cellular signal transdution of protein kinase C and Gi.
Cas No.
72463-77-5
分子式
C24H28O7
分子量
428.481
储存和溶解度
Pyridine, Methanol, etc.:Soluble
Ethanol:Soluble
DMSO:78 mg/mL(182 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years