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Valinomycin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Valinomycin图片
CAS NO:2001-95-8
包装与价格:
包装价格(元)
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
缬氨霉素
NSC 122023
产品介绍
Valinomycin是钾离子选择性运输载体,是一种环状缩酚肽类抗生素。它通过影响生物膜抑制淋巴细胞的扩增,能诱导 CHO 细胞凋亡,也可诱导 PINK1 激活,促进 Parkin 在 Ser65 位点磷酸化。

产品描述

Valinomycin is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin phosphorylation at Ser65.

体内活性

Valinomycin is irritating in contact with eyes and skin. Inhalation of Valinomycin can cause respiratory disturbances and even loss of consciousness. The median lethal dose (LD50) of Valinomycin in mice and rabbits was 2.5 mg/kg and 5 mg/kg, respectively. Valinomycin also has various chronic effects, including central and peripheral nervous system damage, eye damage, lens damage, and corneal damage [3].

Cas No.

2001-95-8

分子式

C54H90N6O18

分子量

1111.32

别名

缬氨霉素;NSC 122023

储存和溶解度

Ethanol:40 mg/mL (36 mM),Need ultrasonic
DMSO:20 mg/mL (18 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years